Publication | Closed Access
Mass spectrometry of bisquinolizidine alkaloids: 2- and 15-substituted derivatives of sparteine and 2- (or 14)-dehydrosparteine
14
Citations
0
References
1998
Year
Bisquinolizidine AlkaloidsBiological Mass SpectrometryOrganic ChemistryChemistryMass Spectral FragmentationsFragmentation PathwaysPharmaceutical ChemistryChemical DerivativeSpectra-structure CorrelationSpectrochemical AnalysisMedicinal Chemistry15-Substituted DerivativesStructure ElucidationAnalytical ChemistryBiochemistryPharmacologyNatural SciencesMass SpectrometryProtein Mass SpectrometryStructural IsomersMedicineDerivative (Chemistry)Molecular FragmentationDrug DiscoveryDrug Analysis
The mass spectral fragmentations of 2-phenylsparteine, 2-(p-tolyl)sparteine, 15-phenylsparteine, 2-phenyl-2-dehydrosparteine, 2-(p-tolyl)-2-dehydrosparteine and 15-phenyl-14-dehydrosparteine were investigated. Fragmentation pathways, elucidation of which was assisted by accurate mass measurements and correlation between the abundances of the M+• and the selected fragment ions of investigated compounds, are discussed. The data obtained create the basis for distinguishing structural isomers. © 1998 John Wiley & Sons, Ltd.