Cantharidin reverses multidrug resistance of human hepatoma HepG2/ADM cells via down-regulation of P-glycoprotein expression

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

Susan P.C. Cole, Gabu Bhardwaj, James H. Gerlach et al. · Science · 1992 · 3.1K citations

Medicine, Molecular Biology, Oncology +16

A multidrug resistance transporter from human MCF-7 breast cancer cells

L. Austin Doyle, Weidong Yang, Lynne V. Abruzzo et al. · Proceedings of the National Academy of Sciences · 1998 · 2.3K citations

Medicine, Oncology, Pharmacology +16

Molecular cloning of cDNAs which are highly overexpressed in mitoxantrone-resistant cells: demonstration of homology to ABC transport genes.

Keisuke Miyake, Lyn A. Mickley, Thomas Litman et al. · PubMed · 1999 · 822 citations · Full text

Medicine, Molecular Biology, Oncology +14

Multidrug Resistance and the Lung Resistance-Related Protein in Human Colon Carcinoma SW-620 Cells

Masaki Kitazono, Tomoyuki Sumizawa, Yuji Takebayashi et al. · JNCI Journal of the National Cancer Institute · 1999 · 185 citations · Full text

Medicine, Molecular Biology, Oncology +16

The multidrug resistance of tumour cells was reversed by tetrandrine in vitro and in xenografts derived from human breast adenocarcinoma MCF-7/adr cells

Liwu Fu, Yun-Xi Zhang, Yong Liang et al. · European Journal of Cancer · 2002 · 155 citations

Medicine, Oncology, Pharmacology +15