Hyper‐reactive PMNs in Fc<i>γ</i>RIIa 131 H/H genotype periodontitis patients

Abstract

The genotyping results confirm previous reports that more periodontal destruction occurs in the H/H genotype than in the H/R or R/R genotype. The functional studies indicate a hyper-reactivity of the H/H-PMN in response to bacteria, which may be one of several pathways leading to more periodontal breakdown.