Host‐ and Microbe‐Related Risk Factors for and Pathophysiology of Fatal<i>Rickettsia conorii</i>Infection in Portuguese Patients

Abstract

Although fatalities and similar clinical manifestations occurred among both groups of patients, the ISF strain was more virulent than the Malish strain. Multivariate analysis revealed that acute renal failure and hyperbilirubinemia were most strongly associated with a fatal outcome.