Effect of High-Pressure Homogenization and Stabilizers on The Physicochemical Properties of Curcumin-Loaded Glycerol Monooleate/Chitosan Nanostructures

Abstract

The process of HPH effectively reduces the PS of the GMO/chitosan nanoemulsions loaded with the hydrophobic drug. The type of stabilizer used affects several physicochemical properties of the GMO/chitosan nanostructures. Compared with PVA, poloxamer 407 is a more effective stabilizer for stabilizing the GMO/chitosan system containing a hydrophobic drug nanoemulsion at low concentrations.