Effect of a lignan (HPMF) on RNA synthesis in the rat uterus

Abstract

Summary. HPMF, at doses of 0·01–1 mg/kg, had no effect on uterine RNA synthesis over a period of 24 h. It significantly depressed oestrogen-stimulated RNA synthesis if administered 22 h before oestradiol but not if given 10 h before or together with the hormone.