Eradicating <i>Helicobacter pylori</i> reduces hypergastrinaemia during long term omeprazole treatment

Abstract

Eradicating H pylori is a means of reducing the rise in gastrin during subsequent long term omeprazole treatment. In view of the potential deleterious effects of hypergastrinaemia it may be appropriate to render patients H pylori negative prior to commencing long-term proton pump inhibitor treatment.