Isolated CNS Whipple disease with a variant of oculofacial—skeletal myorhythmia (OFSM)

Abstract

A 62-year-old woman presented with insidious onset of depressive mood and progressive difficulties with daily activities. She had no diarrhea, abdominal cramps, arthralgia, weight loss, or palpable lymphadenopathy. Physical examination revealed fever, delirium, bilateral upper motor neuron signs, and myorhythmic movements …