PHARMACOKINETIC CONSEQUENCES OF PLASMA PROTEIN BINDING OF DRUGS

Some Physico-Chemical Factors in Drug Action

Bernard B. Brodie, C. Adrian M. Hogben · Journal of Pharmacy and Pharmacology · 1957 · 397 citations

Medicine, Medicinal Chemistry, Pharmacology +9

THE PHYSIOLOGICAL DISPOSITION OF PHENYLBUTAZONE (BUTAZOLIDIN) IN MAN AND A METHOD FOR ITS ESTIMATION IN BIOLOGICAL MATERIAL

J.J. Burns, Rose K. Rose, Theodore Chenkin et al. · Journal of Pharmacology and Experimental Therapeutics · 1953 · 251 citations

Pharmacy, Clinical Pharmacokinetics, Pharmacology +8

Potentiation of Anticoagulant Effect of Warfarin by Phenylbutazone

Paul M. Aggeler, Robert A. O’Reilly, Lois S. Leong et al. · New England Journal of Medicine · 1967 · 237 citations

Medicine, Pharmacology, Pharmacotherapy +14

Clinical pharmacology of the new penicillins: I. The importance of serum protein binding in determining antimicrobial activity and concentration in serum

Calvin M. Kunin · Clinical Pharmacology & Therapeutics · 1966 · 137 citations

Medicine, Pharmacokinetics, Pharmacology +13

Numerical Solution of Nonlinear Pharmacokinetic Equations: Effects of Plasma Protein Binding on Drug Distribution and Elimination

John J. Coffey, Francis J. Bullock, Paul T. Schoenemann · Journal of Pharmaceutical Sciences · 1971 · 58 citations

Pharmacy, Pharmacokinetics, Pharmacology +17