Cyclooxygenase-2 Is an Independent Prognostic Factor in Gastric Cancer and Its Expression Is Regulated by the Messenger RNA Stability Factor HuR - Concepedia

Concepedia

Publication | Closed Access

Cyclooxygenase-2 Is an Independent Prognostic Factor in Gastric Cancer and Its Expression Is Regulated by the Messenger RNA Stability Factor HuR

143

Citations

37

References

2005

Year

Johanna Mrena, Jan‐Patrik Wiksten, Alexandra Thiel, Arto Kokkola, Leena Pohjola, Johan Lundin, Stig Nordling, Ari Ristimäki, Caj Haglund

Clinical Cancer Research

Abstract

High COX-2 is an independent prognostic factor in gastric cancer. Cytoplasmic expression of HuR associates with high COX-2 expression and with reduced survival, and tissue culture experiments show that HuR can regulate expression of COX-2 in gastric cancer cells.

References

	Year	Citations

Page 1