Expression of <i>HYAL1</i> and Survivin RNA as Diagnostic Molecular Markers for Bladder Cancer

Abstract

The detection of urinary HYAL1 and survivin RNA is a promising noninvasive test for bladder cancer early detection. HYAL1 RNA was more sensitive and specific than urine cytology. Semiquantitative reverse transcriptase-polymerase chain reaction is favored for its high sensitivity and specificity.