Induction of eotaxin production by interleukin‐4, interleukin‐13 and lipopolysaccharide by nasal fibroblasts

Abstract

These results suggest that a co-stimulus like LPS is necessary for IL-4 to make a strong induction of eotaxin in eosinophilic inflammations such as nasal polyposis. Modulation by TGF-beta(1) may have important implications for the development of eosinophilic inflammation.