Ischemic preconditioning prevents calpain-mediated impairment of Na+/K+-ATPase activity during early reperfusion☆

Abstract

The results of the present study are consistent with the hypothesis that enhanced recovery of Na+/K+-ATPase activity during reperfusion as a result of attenuated calpain-mediated detachment of the protein from the membrane-cytoskeleton complex contributes to the protection afforded by IPC.