Concepedia

<scp>l</scp>‐Arginine fails to protect against myocardial remodelling in<scp>l</scp>‐NAME‐induced hypertension

Fedor Šimko, Ivan Luptak, Jana Matusková, Kristina Krajcirovicova, Zuzana Sumbalová, Jarmila Kucharská, Anna Gvozdjáková, J Simkó, Pavel Babál, Oľga Pecháňová,

European Journal of Clinical Investigation · 2005 · 27 citations · 41 references

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Abstract

We conclude that L-arginine failed to prevent hypertension, left ventricular hypertrophy and fibrosis development despite restoration of nitric oxide synthase activity in the left ventricle. However, L-arginine prevented the diminution of coenzyme Q levels in the left ventricle.

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