Cyclin-dependent kinase 1 gene expression is associated with poor prognosis in gastric carcinoma.

Abstract

These findings indicate that Cks1, as well as Skp2, regulates the expression level of p27 protein in gastric carcinomas. Cks1 could play an important role in gastric carcinoma progression and would be a novel target for the treatment of gastric carcinomas as well as a strong prognostic marker.