A small GTP-binding protein is frequently overexpressed in peripheral blood mononuclear cells from patients with solid tumours

A Progress Report on the Treatment of 157 Patients with Advanced Cancer Using Lymphokine-Activated Killer Cells and Interleukin-2 or High-Dose Interleukin-2 Alone

Steven A. Rosenberg, Michael T. Lotze, Linda Muul et al. · New England Journal of Medicine · 1987 · 2.8K citations

Pharmacy, Immunology, Oncology +14

Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments

Philippe Chavrier, Robert G. Parton, Hans Peter Hauri et al. · Cell · 1990 · 1.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

In vivo administration of purified human interleukin 2. II. Half life, immunologic effects, and expansion of peripheral lymphoid cells in vivo with recombinant IL 2.

Michael T. Lotze, Yvedt L. Matory, Stephen E. Ettinghausen et al. · The Journal of Immunology · 1985 · 614 citations

Life Sciences, Immunology, Pharmacology +9

GTP-binding mutants of rab1 and rab2 are potent inhibitors of vesicular transport from the endoplasmic reticulum to the Golgi complex.

E J Tisdale, J R Bourne, Roya Khosravi‐Far et al. · The Journal of Cell Biology · 1992 · 500 citations · Full text

Life Sciences, Biology, Molecular Biology +17

The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product

Carmela Calés, John F. Hancock, Christopher J. Marshall et al. · Nature · 1988 · 402 citations

Life Sciences, Genetics, Molecular Biology +13