Effect of Repetitive Arm Cycling Following Botulinum Toxin Injection for Poststroke Spasticity: Evidence From fMRI

Abstract

Increased activity in SII of the contralesional hemisphere and in MISI of the lesioned hemisphere reflect a treatment-induced effect in the paretic arm. It is hypothesized that the increased BOLD activity results from increased afferent information related to the antispastic BTX effect reinforced by training.