Synthesis and Application of 2,6‐Bis(trifluoromethyl)‐4‐pyridyl Phosphanes: The Most Electron‐Poor Aryl Phosphanes with Moderate Bulkiness

Abstract

The poor will be rich: BFPy phosphanes (see scheme) mimic the electronic and steric characters of P(C6F5)3 and PPh3, respectively. These novel ligands showed a large ligand acceleration effect on Stille coupling, the Rh-catalyzed 1,2-addition of aryl boronic acid to unactivated ketones and the asymmetric arylation of N-tosylimine using phenylboronic acid.