Clinical Diabetes · 2005 · 320 citations · 30 references
MedicineGeriatric MedicinePodiatric MedicineDiabetic Foot CareDiabetologyNeuropathologyDiabetes ManagementDiabetic Foot DiseaseDiabetic Foot UlcerationDiabetic NeuropathyPeripheral Neuropathy CarePeripheral Neuropathy ManagementDiabetic Foot DisordersDiabetic Foot PainDiabetic Neuropathic PainDiabetic Peripheral Neuropathy CareGlycemic Control OptimizationPainful Diabetic NeuropathyPeripheral Neuropathy PathophysiologyPodiatric Foot Care
IN BRIEF Diabetic peripheral neuropathy affects up to 50% of older type 2 diabetic patients. Whereas some patients may have extremely painful symptoms, others with a more marked neuropathic deficit may be asymptomatic. Diagnosis requires careful examination of the lower limbs. Management involves establishing that the neuropathy is caused by diabetes instead of more sinister causes and aiming for optimal glycemic control. Medications, usually tricyclic drugs or anticonvulsant agents, may be required. Patients with peripheral neuropathy must be considered at risk of insensate foot ulceration and must receive preventive education and podiatric care.
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