Concepedia

Hypoxic/ischemic conditions induce expression of the putative pro-death gene Clca1 via activation of extrasynaptic N-methyl-d-aspartate receptors

Anna-Sophia Wahl, Bettina Buchthal, Frederik Rode, Signe F. Bomholt, H. Eckehard Freitag, Giles E. Hardingham, Lars Christian B. Rønn, Hilmar Bading

Neuroscience · 2008 · 63 citations · 40 references

DOI

Concepts

References

40

The anticonvulsant MK-801 is a potent N-methyl-D-aspartate antagonist.

Erik H.F. Wong, J A Kemp, Tony Priestley et al. · Proceedings of the National Academy of Sciences · 1986 · 1.8K citations · Full text

, , +15

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

Giles E. Hardingham, Yuko Fukunaga, Hilmar Bading · Nature Neuroscience · 2002 · 1.7K citations

, , +17

Regulation of Gene Expression in Hippocampal Neurons by Distinct Calcium Signaling Pathways

Hilmar Bading, David D. Ginty, Michael E. Greenberg · Science · 1993 · 1.2K citations

, , +17

Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.

James E. Huettner, Bruce P. Bean · Proceedings of the National Academy of Sciences · 1988 · 755 citations · Full text

, , +17

Systemic administration of MK-801 protects against ischemia-induced hippocampal neurodegeneration in the gerbil

R. Gill, AC Foster, GN Woodruff · Journal of Neuroscience · 1987 · 643 citations · Full text

, , +17