Publication | Closed Access
A Convenient Synthesis of Cyanine Dyes: Reagents for the Labeling of Biomolecules
69
Citations
43
References
2008
Year
Bioorganic ChemistryEngineeringAbstract Four TetramethylindoMolecular BiologyOrganic ChemistryChemical BiologyNucleic Acid ChemistryConvenient SynthesisDyeingOne‐pot ProcedureBiochemistryDiversity-oriented SynthesisBioconjugationOligonucleotideDye AssemblyNatural Product SynthesisBio-orthogonal ChemistryBiomolecular EngineeringNatural SciencesCyanine DyesPigment
Abstract Four tetramethylindo(di)carbocyanine‐derived carboxylicacids have been prepared using a modified one‐pot procedure for the dye assembly. The acids were converted into oxysuccinimide esters and phosphoramidite reagents. The efficiency of the reagents in the labeling of oligonucleotides and proteins has been demonstrated. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)
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