Concepedia

Intratumoral Administration of Methotrexate Bound to Activated Carbon Particles: Antitumor Effectiveness against Human Colon Carcinoma Xenografts and Acute Toxicity in Mice

Yuen Nakase, Akeo Hagiwara, Syuichi Kin, Kenichirou Fukuda, Tadao Ito, Tsuyoshi Takagi, Jyunshin Fujiyama, Chohei Sakakura, Eigo Otsuji, Hisakazu Yamagishi

Journal of Pharmacology and Experimental Therapeutics · 2004 · 19 citations · 17 references

DOI

Concepts

References

17

Synthesis of Polyamidoamine Dendrimers Having Poly(ethylene glycol) Grafts and Their Ability To Encapsulate Anticancer Drugs

Chie Kojima, Kenji Kono, Kazuo Maruyama et al. · Bioconjugate Chemistry · 2000 · 655 citations

, , +17

In vitro and in vivo antitumor activity of methotrexate conjugated to human serum albumin in human cancer cells.

Katja Wosikowski, Elfi Biedermann, Benno Rattel et al. · PubMed · 2003 · 115 citations

, , +14

Phase I trial of methotrexate-albumin in a weekly intravenous bolus regimen in cancer patients. Phase I Study Group of the Association for Medical Oncology of the German Cancer Society.

G. Hartung, G. Stehle, H. Sinn et al. · PubMed · 1999 · 89 citations

, , +16

A phase II trial of methotrexate-human serum albumin (MTX-HSA) in patients with metastatic renal cell carcinoma who progressed under immunotherapy

Vis A., Ate van der Gaast, Bas van Rhijn et al. · Cancer Chemotherapy and Pharmacology · 2002 · 73 citations

, , +13

Methotrexate cytotoxicity for L5178Y/Asn- lymphoblasts: relationship of dose and duration of exposure to tumor cell viability.

Debbi Keefe, Robert L. Capizzi, Seth A. Rudnick · PubMed · 1982 · 62 citations

, , +14