Concepedia

Chemical Radioprotection of Mammalian Chromosomes <i>in Vivo:</i> Radioprotection of Rat Bone-marrow Chromosomes with a Single Prophylactic Dose of AET

J. P. Chaudhuri, H. Langendorff

International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine · 1968 · 20 citations · 5 references

DOI

Concepts

Abstract

SummaryOf three prophylactic doses of AET pre-treatment 240 mg/kg gave the best protection against chromosome aberrations induced by 640 R of x-rays in rat bone-marrow, DRF values being 1·23–1·36. Even this low DRF at the level of early cellular lesion may considerably influence in favour of survival of sublethally-irradiated animals.

References

5

Mechanism of Action of Aminothiol Radioprotectors

P.E. Brown · Nature · 1967 · 109 citations · Full text

, , +12

The effect of cysteamine, cystamine and hypoxia on mortality and bone marrow chromosome aberrations in mice after total body roentgen irradiation

F Devik, F. Lothe · Acta Radiologica · 1955 · 38 citations

, , +14

Cellular Aspects of the Mammalian Radiation Syndrome: II. Cell Depletion in Bone Marrow, Spleen, and Thymus of Young Mice

Theodore T. Puck · Radiation Research · 1966 · 28 citations

, , +17

Thiol content of calf thymus histone fractions

Egil Jellum · Biochimica et Biophysica Acta (BBA) - General Subjects · 1966 · 20 citations

, , +8

Mechanism of the Protective Action of GED against Radiation Damage to DNA

George Kollmann, Bernard Shapiro, David W. Martin · Radiation Research · 1967 · 16 citations

, , +17