In Vivo Imaging of⁶⁴Cu-Labeled Polymer Nanoparticles Targeted to the Lung Endothelium

Abstract

The use of small-animal PET to track (64)Cu-labeled nanostructures in vivo shows potential as a strategy for the preclinical screening of new NP drug delivery agents targeting the lung endothelium and other tissues. Future design optimization to prolong the stability of the radiolabel in vivo will further improve this promising approach.