Effects of platelet-derived growth factor-BB on the metabolic function and morphologic features of equine tendon in explant culture

Abstract

Results suggest that rhPDGF-BB use may be of benefit in the repair of equine tendon, particularly through induction of collagen type I mRNA. Positive autoinductive effects of PDGF-BB in equine SDFT explants were detected early following culture medium supplementation, but these diminished with time.