Peutz-Jeghers syndrome associated with primary malignant melanoma of the rectum

Abstract

An 85-year-old Chinese woman was found to have mucocutaneous pigmentation involving the lips, buccal mucosa, hard palate and the buttocks when she presented with primary malignant melanoma of the rectum. Multiple brown-black pigmentation was also noted in the anal canal and the adjacent mucosa surrounding the tumour. This is the first report of Peutz-Jeghers syndrome associated with malignant melanoma of the rectum.