Concepedia

Refining the Perfusion–Diffusion Mismatch Hypothesis

Kenneth Butcher, Mark Parsons, Lachlan MacGregor, P. Alan Barber, J. B. Chalk, Christopher Bladin, Christopher Levi, Thomas Kimber, David Schultz, John Fink,

Stroke · 2005 · 222 citations · 19 references

DOI

Abstract

Deconvolution and application of PWI thresholds provide more conservative estimates of tissue at risk and decrease the frequency of mismatch accordingly. The precise definition may not be critical; however, because reperfusion alters tissue fate irrespective of mismatch.

References

19

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Tobias Neumann‐Haefelin, Hans‐Jörg Wittsack, Frank Wenserski et al. · Stroke · 1999 · 574 citations · Full text

Diffusion‐ and perfusion‐weighted MRI response to thrombolysis in stroke

Mark Parsons, P. Alan Barber, J. B. Chalk et al. · Annals of Neurology · 2001 · 355 citations