Long-Term Therapy With Low-Dose Isotretinoin for Prevention of Basal Cell Carcinoma: A Multicenter Clinical Trial

Joseph A. Tangrea, B. K. Edwards, Philip R. Taylor, Anne M. Hartman, Gary L. Peck, Stuart J. Salasche, P. A. Menon, Paul Benson, J. Ramsey Mellette, Marshall A. Guill,

JNCI Journal of the National Cancer Institute · 1992 · 173 citations · 0 references

DOI

Abstract

The toxicity associated with the long-term administration of isotretinoin, even at the low dose used in this trial, must be weighted in planning future prevention trials.