A Novel Tumor Necrosis Factor–mediated Mechanism of Direct Epithelial Sodium Channel Activation - Concepedia

Concepedia

Publication | Open Access

A Novel Tumor Necrosis Factor–mediated Mechanism of Direct Epithelial Sodium Channel Activation

DOI Full Paper Access

58

Citations

50

References

2014

Year

István Czikora, Abdel A. Alli, Hui-Fang Bao, David Kaftan, Supriya Sridhar, Hans‐Jürgen Apell, Boris Gorshkov, Richard E. White, Astrid Zimmermann, Albrecht Wendel,

American Journal of Respiratory and Critical Care Medicine

Abstract

These results demonstrate a novel TNF-mediated mechanism of direct ENaC activation and indicate a physiological role for the lectin-like domain of TNF in the resolution of alveolar edema during inflammation.

References

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