Concepedia

Integrative Genomic and Proteomic Analyses Identify Targets for Lkb1-Deficient Metastatic Lung Tumors

Julián Carretero, Takeshi Shimamura, Klarisa Rikova, Autumn L. Jackson, Matthew D. Wilkerson, Christa L. Borgman, Matthew S. Buttarazzi, Benjamin A. Sanofsky, Kate L. McNamara, K. Brandstetter,

Cancer Cell · 2010 · 260 citations · 35 references

DOIFull text

Open access

Concepts

References

35

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 56.7K citations · Full text

, , +12

An embryonic stem cell–like gene expression signature in poorly differentiated aggressive human tumors

Ittai Ben‐Porath, Matthew Thomson, Vincent J. Carey et al. · Nature Genetics · 2008 · 2.6K citations · Full text

, , +16

Global Survey of Phosphotyrosine Signaling Identifies Oncogenic Kinases in Lung Cancer

Klarisa Rikova, Ailan Guo, Qingfu Zeng et al. · Cell · 2007 · 2.3K citations · Full text

, , +16

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

Andrea Bild, Guang Yao, Jeffrey T. Chang et al. · Nature · 2005 · 2.1K citations

, , +14

Analysis of lung tumor initiation and progression using conditional expression of oncogenic <i>K-ras</i>

Erica L. Jackson, Nicholas A. Willis, Kim L. Mercer et al. · Genes & Development · 2001 · 2K citations · Full text

, , +17