Concepedia

Facile Synthesis of β‐Azidocyclopropanecarboxylates by MIRC Reaction

Jiangtao Su, Guofu Qiu, Shucai Liang, Xianming Hu

Synthetic Communications · 2005 · 17 citations · 9 references

DOI

Concepts

Abstract

Abstract Two β‐azidocyclopropanecarboxylates are readily synthesized from β‐bromoalkyliden malonates via a Michael–initiated ring closure (MIRC) reaction in moderate yields, which are regarded as precursors of β‐aminocyclopropanecarboxylic acids.

References

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Straightforward Synthesis of 1-Amino-2,2-dialkylcyclopropanecarboxylic Acids via Selective Saponification of 2,2-Dialkylcyclopropane-1,1-dicarboxylic Esters and Curtius Rearrangement

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