Regulating Supramolecular Function in Membranes: Calixarenes that Enable or Inhibit Transmembrane Cl⁻ Transport

Abstract

Self-assembled transporter: Self-association of a partial-cone calixarene amide provides membrane-active aggregates that enable the transport of chloride anions across phospholipid membranes (see picture). Additionally, a regulatory system is described, wherein an inactive calixarene analogue inhibits the active chloride transporter. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z504489_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.