Clinical Infectious Diseases · 2006 · 75 citations · 19 references
MedicineNephrologyPathologyRenal PathologyRenal PathophysiologyVirologyAntiretroviral TherapyHiv DiagnosisImmune-mediated Renal DiseaseRenal DiseaseRenal Vascular DiseaseRna-based DiagnosticsHistopathological DiagnosisHistopathological EvaluationHiv Nucleic Acid TestingHypertensive Vascular DiseaseRenal Biopsy FindingsRenal SurvivalViral Load AssaysViral Renal Disease
To determine the value of human immunodeficiency virus type 1 (HIV-1) RNA level in distinguishing HIV-associated nephropathy from non-HIV-associated nephropathy renal pathological conditions, we retrospectively compared renal histopathological findings for 86 HIV-infected patients according to HIV-1 RNA levels. We found that HIV-associated nephropathy was unlikely among patients with HIV-1 RNA levels <400 copies/mL. Hypertensive vascular disease surpassed HIV-associated nephropathy as the most common renal pathological finding among the entire cohort. HIV-1 RNA level did not correlate with renal survival.
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Pathology of HIV-associated nephropathy: A detailed morphologic and comparative study
Vivette D. D’Agati, Jung-Il Suh, Laura Carbone et al. · Kidney International · 1989 · 374 citations · Full text
Medicine, Nephrology, Pathology +13