Concepedia

Publication | Open Access

Profilin-1 suppresses tumorigenicity in pancreatic cancer through regulation of the SIRT3-HIF1α axis

DOIFull Paper Access

78

Citations

26

References

2014

Year

Wantong Yao, Shunrong Ji, Yi Qin, Jingxuan Yang, Jin Xu, Bo Zhang, Wenyan Xu, Jiang Liu, Si Shi, Liang Liu,
Molecular Cancer

Abstract

Our data suggest that Pfn1 is a tumor suppressor in pancreatic cancer that acts via a novel mechanism of regulating the SIRT3-HIF1α axis, independently of its cytoskeleton-related activity.

References

YearCitations

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