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Steroid 5α-Reductase Isozymes I and II in Recurrent Prostate Cancer

DOIFull Paper Access

173

Citations

39

References

2005

Year

Mark Titus, Christopher W. Gregory, O. Harris Ford, Michael J. Schell, Susan J. Maygarden, James L. Mohler
Clinical Cancer Research

Abstract

Expression levels and isozyme activity shifts from S5alphaRII toward S5alphaRI in recurrent prostate cancer. Dual inhibition of S5alphaRI and S5alphaRII should reduce dihydrotestosterone biosynthesis and may prevent or delay growth of recurrent prostate cancer.

References

YearCitations

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