Randomized, double‐blind study of pramipexole with placebo and bromocriptine in advanced Parkinson's disease

Yoshikuni Mizuno, Nobuo Yanagisawa, Sadako Kuno, Mitsutoshi Yamamoto, Kazuko Hasegawa, Hideki Origasa, Hisayuki Kowa

Movement Disorders · 2003 · 76 citations · 16 references

Concepts

Abstract

We compared the efficacy and safety of pramipexole (PPX) with placebo in the treatment of advanced Parkinson's disease (PD) as an adjunct to levodopa. A bromocriptine (BR) group was included to enable determination of the noninferiority of PPX relative to BR as the standard treatment.

References

16