Expansions of CD8CD28− and CD8TcRVβ5.2 T Cells in Peripheral Blood of Heavy Alcohol Drinkers

Abstract

This study showed that under active ethanol consumption, expansions of discrete CD8+ T-cell subsets occur within the CD8+ T-cell pool, that molecules of the MHC-class I locus seem to influence the extent of the expansions, and that high numbers of CD8+CD28- T cells are associated with low levels of liver enzymes in AHD.