Contribution of Gene Sequence Variations of the Hepatic Cytochrome P450 3A4 Enzyme to Variability in Individual Responsiveness to Clopidogrel - Concepedia

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Publication | Open Access

Contribution of Gene Sequence Variations of the Hepatic Cytochrome P450 3A4 Enzyme to Variability in Individual Responsiveness to Clopidogrel

DOI Full Paper Access

228

Citations

25

References

2006

Year

Dominick J. Angiolillo, Antonio Fernández‐Ortíz, Esther Bernardo, Celia Ramírez, Ugo Cavallari, Elisabetta Trabetti, Manel Sabaté, Rosana Hernández, Raúl Moreno, Javier Escaned,

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

The IVS10+12G>A polymorphism of the CYP3A4 gene modulates platelet activation in patients treated with clopidogrel and may therefore contribute to clopidogrel response variability.

References

	Year	Citations

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