An Investigation of Sclerema Neonatorum; with Special Reference to the Chemistry of the Subcutaneous Tissues: (Part II.)

Abstract

CIIEMICAL INNVESTIGATION OF SUBCUTANEOUS TISSUES.A few preliminary determinations only were nmade by McNee in Cases I. and IT.These will be given first.As a result of the experience gained in these two eases, a definite plan of campaign was outlined for the investigation of Cases III. and IV.Case V. recovered spontaneously and no biopsy was made.A. Cases I. a-1(1 II.and Controls.The fat was melted otut of a imiass-of subcutaneous fat, and dried.TIhe melting point of this separated fat was taken by the capillary method; and the, iodine value was determined by Hubl's method.Case I. Control I. Case II.Control II.Age ... ... ... 6 weeks 1 year 12 weeks 9 weeks M.P. of separated fat, OC.50 5 33-5 38 5 32 5Iodine value of ditto (Hubl) .42 1 45-7 52 0 57-5 Control I. died fromn capillary bronchitis and Control II.from gastroenteritis.Cholesterol determin.ationswere made in Case I. and Control I. with the following results (mnethod of Windaus) : Case I.Control I.Percentage of Free cholesterol ... ...