Sigma-1 Receptor Activation Prevents Intracellular Calcium Dysregulation in Cortical Neurons during in Vitro Ischemia

Purification, molecular cloning, and expression of the mammalian sigma1-binding site.

Markus Hanner, Fabian F. Moebius, Astrid Flandorfer et al. · Proceedings of the National Academy of Sciences · 1996 · 905 citations

Drug Target, Sigma1-binding Site, Molecular Biology +17

Ca(2+) signaling via sigma(1)-receptors: novel regulatory mechanism affecting intracellular Ca(2+) concentration.

T. HAYASHI, Tangui Maurice, Tsung-Ping Su · PubMed · 2000 · 295 citations

Pertussis Toxin, Cellular Physiology, Signaling Pathway +21

Characterization of two novel σ receptor ligands: antidystonic effects in rats suggest σ receptor antagonism

Rae R. Matsumoto, Wayne D. Bowen, Michael A. Tom et al. · European Journal of Pharmacology · 1995 · 266 citations

Molecular Pharmacology, Antidystonic Effects, Medicine +8

Periodic synchronized bursting and intracellular calcium transients elicited by low magnesium in cultured cortical neurons

Hugh P. C. Robinson, Masahiro Kawahara, Yasuhiko Jimbo et al. · Journal of Neurophysiology · 1993 · 242 citations

Synaptic Transmission, Neurotransmission, Intracellular Calcium Transients +19

Mechanisms Underlying the Rapid Depolarization Produced by Deprivation of Oxygen and Glucose in Rat Hippocampal CA1 Neurons In Vitro

E. Tanaka, S. Yamamoto, Yoshihisa Kudo et al. · Journal of Neurophysiology · 1997 · 203 citations