Postinfarction Treatment With an Adenoviral Vector Expressing Hepatocyte Growth Factor Relieves Chronic Left Ventricular Remodeling and Dysfunction in Mice - Concepedia

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Postinfarction Treatment With an Adenoviral Vector Expressing Hepatocyte Growth Factor Relieves Chronic Left Ventricular Remodeling and Dysfunction in Mice

112

Citations

20

References

2003

Year

Yiwen Li, Genzou Takemura, Ken-ichiro Kosai, Kentaro Yuge, Satoshi Nagano, Esaki Masayasu, Kazuko Goto, Tomoyuki Takahashi, Kenji Hayakawa, Masahiko Koda,

Abstract

Postinfarction HGF gene therapy improved LV remodeling and dysfunction through hypertrophy of cardiomyocytes, infarct wall thickening, preservation of vessels, and antifibrosis. These findings imply a novel therapeutic approach against postinfarction heart failure.

References

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