Aquaporin 4‐specific T cells in neuromyelitis optica exhibit a Th17 bias and recognize <i>Clostridium</i> ABC transporter

Abstract

AQP4-specific T-cell responses are amplified in NMO, exhibit a Th17 bias, and display cross-reactivity to a protein of an indigenous intestinal bacterium, providing new perspectives for investigating NMO pathogenesis.