RGS2-Mediated Intracellular Ca2+ Level Plays a Key Role in the Intracellular Replication of Brucella abortus Within Phagocytes

Abstract

These results indicate that B. abortus infection induces host RGS2 expression and that up-regulation of [Ca(2+)](i) levels is an essential factor for the intracellular survival of B. abortus within phagocytes.