European Society of Gastrointestinal Endoscopy (ESGE)Guideline: Prophylaxis of post-ERCP pancreatitis

TLDR

Pancreatitis is the most common complication of ERCP, with patient‑ and procedure‑related risk factors. The guideline aims to identify high‑risk patients and provide graded recommendations to prevent post‑ERCP pancreatitis. PEP prevention involves NSAID administration, specific cannulation techniques, and temporary pancreatic stent placement.

Abstract

Pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). Risk factors for post-ERCP pancreatitis (PEP) are both patient-related and procedure-related. Identification of patients at high risk for PEP is important in order to target prophylactic measures. Prevention of PEP includes administration of nonsteroidal inflammatory drugs (NSAIDs), use of specific cannulation techniques, and placement of temporary pancreatic stents. The aim of this guideline commissioned by the European Society of Gastrointestinal Endoscopy (ESGE) is to provide practical, graded, recommendations for the prevention of PEP.