Concepedia

Publication | Closed Access

Cyclooxygenase-2 Activation Mediates the Proangiogenic Effect of Nitric Oxide in Colorectal Cancer

DOI

132

Citations

37

References

2004

Year

Fabio Cianchi, C Cortesini, Ornella Fantappiè, Luca Messerini, Iacopo Sardi, Nadia Lasagna, Federico Perna, Valentina Fabbroni, Annamaria Di Felice, Giuliano Perigli,
Clinical Cancer Research

Abstract

Our data showed a prominent role of nitric oxide in stimulating COX-2 activity in colorectal cancer. This interaction is likely to produce a cooperative effect in promoting angiogenesis through PGE(2)-mediated increase in VEGF production.

References

YearCitations

Page 1