Familial ligand-defective apolipoprotein B-100: detection, biochemical features and haplotype analysis of the R3531C mutation in the UK

Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge

William T. Friedewald, Robert I. Levy, Donald S. Fredrickson · Clinical Chemistry · 1972 · 32.5K citations

Life Sciences, Biochemistry, Clinical Biochemistry +14

A simple salting out procedure for extracting DNA from human nucleated cells

S.A. Miller, Dale D. Dykes, Herbert F. Polesky · Nucleic Acids Research · 1988 · 20.6K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +8

Risk of fatal coronary heart disease in familial hypercholesterolaemia. Scientific Steering Committee on behalf of the Simon Broome Register Group.

Margaret Thorogood · BMJ · 1991 · 817 citations · Full text

Medicine, Cardiology, Health Sciences +17

Association between a specific apolipoprotein B mutation and familial defective apolipoprotein B-100.

L. F. SORIA, E H Ludwig, Howard R. G. Clarke et al. · Proceedings of the National Academy of Sciences · 1989 · 636 citations · Full text

Medicine, Genetics, Molecular Genetics +16

Restriction sites containing CpG show a higher frequency of polymorphism in human DNA

David J.P. Barker, Markus Schäfer, R. White · Cell · 1984 · 582 citations

Life Sciences, Genetics, Molecular Genetics +9