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Transforming Growth Factor-β–Activated Kinase 1 Regulates Angiogenesis via AMP-Activated Protein Kinase-α1 and Redox Balance in Endothelial Cells

DOIFull Paper Access

42

Citations

37

References

2013

Year

Nina Zippel, Randa Abdel Malik, Timo Frömel, Rüdiger Popp, Elke Bess, Boris Strilić, Nina Wettschureck, Ingrid Fleming, Beate Fißlthaler
Arteriosclerosis Thrombosis and Vascular Biology

Abstract

These results establish TAK1 as an AMPKα1 kinase that regulates vascular endothelial growth factor-induced and cytokine-induced angiogenesis by modulating SOD2 expression and the superoxide anion:hydrogen peroxide balance.

References

YearCitations

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