<sup>11</sup>C-CUMI-101, a PET Radioligand, Behaves as a Serotonin 1A Receptor Antagonist and Also Binds to α<sub>1</sub>Adrenoceptors in Brain - Concepedia

Concepedia

Publication | Open Access

<sup>11</sup>C-CUMI-101, a PET Radioligand, Behaves as a Serotonin 1A Receptor Antagonist and Also Binds to α<sub>1</sub>Adrenoceptors in Brain

DOI Full Paper Access

23

Citations

17

References

2014

Year

Saurav Shrestha, Jeih‐San Liow, Shuiyu Lu, Kimberly J. Jenko, Robert L. Gladding, Per Svenningsson, Cheryl L. Morse, Sami S. Zoghbi, Victor W. Pike, Robert B. Innis

Journal of Nuclear Medicine

Abstract

CUMI-101 behaves as a 5-HT1A receptor antagonist in primate brain, with significant, regional-dependent α1 adrenoceptor cross-reactivity, limiting its potential use as a PET radioligand in humans.

References

	Year	Citations

Page 1