Congenital Hypothyroidism: Influence of Disease Severity and<scp>l</scp>-Thyroxine Treatment on Intellectual, Motor, and School-Associated Outcomes in Young Adults

Abstract

Long-term outcome revealed enduring cognitive and motor deficits in young adults with CH relative to control subjects. Verbal functions and Arithmetic were associated with L-thyroxine treatment variables, suggesting that more optimal treatment might be possible. Motor outcome was associated with CH severity, indicating a prenatal effect.