Prognostic Role of <i>PIK3CA</i> Mutation in Colorectal Cancer: Cohort Study and Literature Review

Abstract

Coexistence of PIK3CA (the PI3K p110α subunit) exon 9 and 20 mutations, but not PIK3CA mutation in either exon 9 or 20 alone, is associated with poor prognosis of colorectal cancer patients.